The Lisboa Hotel is situated centrally within the central business district. Guests of this Macau hotel will be able to walk to corporate addresses as well as entertainment venues, dining options, and shopping centers. The Macau International Airport is fifteen minutes away from the Lisboa Hotel. Additional travel options include the Macau Hong Kong Ferry, which is just five minutes away, and a selection of public transportation options.

Guestrooms at the Lisboa Hotel provide such amenities as satellite television with on-demand movies, air-conditioning, in-room safes, radios, and private bathrooms with bathrobes. There are one thousand standard rooms and suites at the hotel.

Designed to accommodate both business and leisure guests, the Lisboa Hotel provides guests with an array of amenities. Guest services include a selection of restaurants, a bar, a meeting room, a banquet hall, and a business center. Additionally, the hotel offers a fitness center, a swimming pool, a currency exchange service, a jewelry shop, a nightclub, a spa, and an on-site casino, which is open twenty-four hours a day.